Ferritin Light Chain Confers Protection Against Sepsis-Induced Inflammation and Organ Injury

Despite the prevalence and recognition of its detrimental impact, clinical complications of sepsis remain a major challenge. Here, we investigated the effects of myeloid ferritin heavy chain (FtH) in regulating the pathogenic sequelae of sepsis. We demonstrate that deletion of myeloid FtH leads to p...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zarjou, Abolfazl, Black, Laurence M., McCullough, Kayla R., Hull, Travis D., Esman, Stephanie K., Boddu, Ravindra, Varambally, Sooryanarayana, Chandrashekar, Darshan S., Feng, Wenguang, Arosio, Paolo, Poli, Maura, Balla, Jozsef, Bolisetty, Subhashini
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371952/
https://ncbi.nlm.nih.gov/pubmed/30804939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00131
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