Ferritin Light Chain Confers Protection Against Sepsis-Induced Inflammation and Organ Injury

Despite the prevalence and recognition of its detrimental impact, clinical complications of sepsis remain a major challenge. Here, we investigated the effects of myeloid ferritin heavy chain (FtH) in regulating the pathogenic sequelae of sepsis. We demonstrate that deletion of myeloid FtH leads to p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Zarjou, Abolfazl, Black, Laurence M., McCullough, Kayla R., Hull, Travis D., Esman, Stephanie K., Boddu, Ravindra, Varambally, Sooryanarayana, Chandrashekar, Darshan S., Feng, Wenguang, Arosio, Paolo, Poli, Maura, Balla, Jozsef, Bolisetty, Subhashini
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371952/
https://ncbi.nlm.nih.gov/pubmed/30804939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00131
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