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Roles of Cytochrome P450 in Metabolism of Ethanol and Carcinogens

Cytochrome P450 (P450) enzymes are involved in the metabolism of carcinogens, as well as drugs, steroids, vitamins, and other classes of chemicals. P450s also oxidize ethanol, in particular P450 2E1. P450 2E1 oxidizes ethanol to acetaldehyde and then to acetic acid, roles also played by alcohol and...

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Bibliografiske detaljer
Udgivet i:Adv Exp Med Biol
Main Authors: Guengerich, F. Peter, Avadhani, Narayan G.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371814/
https://ncbi.nlm.nih.gov/pubmed/30362088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-98788-0_2
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