Combination Therapy With Fingolimod and Neural Stem Cells Promotes Functional Myelination in vivo Through a Non-immunomodulatory Mechanism

Myelination, which occurs predominantly postnatally and continues throughout life, is important for proper neurologic function of the mammalian central nervous system (CNS). We have previously demonstrated that the combination therapy of fingolimod (FTY720) and transplanted neural stem cells (NSCs)...

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Pubblicato in:Front Cell Neurosci
Autori principali: Zhang, Yuan, Lu, Xin-Yu, Ye, Ze-Qin, Ciric, Bogoljub, Ma, Cun-Gen, Rostami, Abdolmohamad, Li, Xing, Zhang, Guang-Xian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371042/
https://ncbi.nlm.nih.gov/pubmed/30804753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00014
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