Effect of Fingolimod on Neural Stem Cells: A Novel Mechanism and Broadened Application for Neural Repair

Inflammatory demyelination and axonal damage of the CNS are hallmarks of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Fingolimod (FTY720), the first FDA-approved oral medication for MS, suppresses acute disease but is less effective at the chronic st...

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Foilsithe in:Mol Ther
Main Authors: Zhang, Yuan, Li, Xing, Ciric, Bogoljub, Ma, Cun-Gen, Gran, Bruno, Rostami, Abdolmohamad, Zhang, Guang-Xian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2017
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368668/
https://ncbi.nlm.nih.gov/pubmed/28153091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.12.008
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