Effect of Fingolimod on Neural Stem Cells: A Novel Mechanism and Broadened Application for Neural Repair

Inflammatory demyelination and axonal damage of the CNS are hallmarks of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Fingolimod (FTY720), the first FDA-approved oral medication for MS, suppresses acute disease but is less effective at the chronic st...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Zhang, Yuan, Li, Xing, Ciric, Bogoljub, Ma, Cun-Gen, Gran, Bruno, Rostami, Abdolmohamad, Zhang, Guang-Xian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5368668/
https://ncbi.nlm.nih.gov/pubmed/28153091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2016.12.008
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