Residual Activatability of Circulating Tfh17 Predicts Humoral Response to Thymodependent Antigens in Patients on Therapeutic Immunosuppression

The generation of antibodies against protein antigens (such as donor-specific HLA molecules) requires that T follicular helper cells (Tfh) provide help to B cells. Immunosuppressive (IS) armamentarium prevents T cell activation, yet a significant proportion of renal transplant patients develop donor...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Dahdal, Suzan, Saison, Carole, Valette, Martine, Bachy, Emmanuel, Pallet, Nicolas, Lina, Bruno, Koenig, Alice, Monneret, Guillaume, Defrance, Thierry, Morelon, Emmanuel, Thaunat, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370621/
https://ncbi.nlm.nih.gov/pubmed/30804950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.03178
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