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Bioengineered Let-7c Inhibits Orthotopic Hepatocellular Carcinoma and Improves Overall Survival with Minimal Immunogenicity

Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related deaths, warranting better therapies. Restoration of tumor-suppressive microRNAs depleted in hepatocellular carcinoma represents a new therapeutic strategy. Herein, we sought to identify a potent microRNA (miRNA) agent that coul...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Principais autores: Jilek, Joseph L., Zhang, Qian-Yu, Tu, Mei-Juan, Ho, Pui Yan, Duan, Zhijian, Qiu, Jing-Xin, Yu, Ai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370598/
https://ncbi.nlm.nih.gov/pubmed/30753993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.01.007
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