Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy

Noncoding RNAs (ncRNAs) produced in live cells may better reflect intracellular ncRNAs for research and therapy. Attempts were made to produce biologic ncRNAs, but at low yield or success rate. Here we first report a new ncRNA bioengineering technology using more stable ncRNA carrier (nCAR) containi...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Ho, Pui Yan, Duan, Zhijian, Batra, Neelu, Jilek, Joseph L., Tu, Mei-Juan, Qiu, Jing-Xin, Hu, Zihua, Wun, Theodore, Lara, Primo N., DeVere White, Ralph W., Chen, Hong-Wu, Yu, Ai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Drug Discovery and Translational Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931433/
https://ncbi.nlm.nih.gov/pubmed/29602831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.247775
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