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Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer Therapy

Noncoding RNAs (ncRNAs) produced in live cells may better reflect intracellular ncRNAs for research and therapy. Attempts were made to produce biologic ncRNAs, but at low yield or success rate. Here we first report a new ncRNA bioengineering technology using more stable ncRNA carrier (nCAR) containi...

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Bibliografske podrobnosti
izdano v:J Pharmacol Exp Ther
Main Authors: Ho, Pui Yan, Duan, Zhijian, Batra, Neelu, Jilek, Joseph L., Tu, Mei-Juan, Qiu, Jing-Xin, Hu, Zihua, Wun, Theodore, Lara, Primo N., DeVere White, Ralph W., Chen, Hong-Wu, Yu, Ai-Ming
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5931433/
https://ncbi.nlm.nih.gov/pubmed/29602831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.247775
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