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Network hubs affect evolvability

The regulatory processes in cells are typically organized into complex genetic networks. However, it is still unclear how this network structure modulates the evolution of cellular regulation. One would expect that mutations in central and highly connected modules of a network (so-called hubs) would...

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Veröffentlicht in:PLoS Biol
Hauptverfasser: Helsen, Jana, Frickel, Jens, Jelier, Rob, Verstrepen, Kevin J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370235/
https://ncbi.nlm.nih.gov/pubmed/30699103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000111
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