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Preferential protection of protein interaction network hubs in yeast: Evolved functionality of genetic redundancy

The widely observed dispensability of duplicate genes is typically interpreted to suggest that a proportion of the duplicate pairs are at least partially redundant in their functions, thus allowing for compensatory affects. However, because redundancy is expected to be evolutionarily short lived, th...

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Autors principals: Kafri, Ran, Dahan, Orna, Levy, Jonathan, Pilpel, Yitzhak
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234123/
https://ncbi.nlm.nih.gov/pubmed/18216251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711043105
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