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Network hubs affect evolvability

The regulatory processes in cells are typically organized into complex genetic networks. However, it is still unclear how this network structure modulates the evolution of cellular regulation. One would expect that mutations in central and highly connected modules of a network (so-called hubs) would...

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Bibliographic Details
Published in:PLoS Biol
Main Authors: Helsen, Jana, Frickel, Jens, Jelier, Rob, Verstrepen, Kevin J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6370235/
https://ncbi.nlm.nih.gov/pubmed/30699103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000111
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