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Differential mutagenicity of riddelliine in liver endothelial and parenchymal cells of transgenic big blue rats
Riddelliine is a naturally occurring pyrrolizidine alkaloid that induces liver hemangiosarcomas in rats and mice. We previously reported higher levels of DNA adducts in liver endothelial cells than in liver parenchymal cells of riddelliine-treated mice and rats [Cancer Lett. 193 (2003) 119], suggest...
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| Publicado en: | Cancer Lett |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6370022/ https://ncbi.nlm.nih.gov/pubmed/15488633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2004.06.013 |
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