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An evolutionary compass for detecting signals of polygenic selection and mutational bias

Selection and mutation shape the genetic variation underlying human traits, but the specific evolutionary mechanisms driving complex trait variation are largely unknown. We developed a statistical method that uses polarized genome‐wide association study (GWAS) summary statistics from a single popula...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Evol Lett
Päätekijät: Uricchio, Lawrence H., Kitano, Hugo C., Gusev, Alexander, Zaitlen, Noah A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369964/
https://ncbi.nlm.nih.gov/pubmed/30788143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/evl3.97
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