More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

The genus Legionella comprises 65 species, among which Legionella pneumophila is a human pathogen causing severe pneumonia. To understand the evolution of an environmental to an accidental human pathogen, we have functionally analyzed 80 Legionella genomes spanning 58 species. Uniquely, an immense r...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gomez-Valero, Laura, Rusniok, Christophe, Carson, Danielle, Mondino, Sonia, Pérez-Cobas, Ana Elena, Rolando, Monica, Pasricha, Shivani, Reuter, Sandra, Demirtas, Jasmin, Crumbach, Johannes, Descorps-Declere, Stephane, Hartland, Elizabeth L., Jarraud, Sophie, Dougan, Gordon, Schroeder, Gunnar N., Frankel, Gad, Buchrieser, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369783/
https://ncbi.nlm.nih.gov/pubmed/30659146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808016116
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