More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

The genus Legionella comprises 65 species, among which Legionella pneumophila is a human pathogen causing severe pneumonia. To understand the evolution of an environmental to an accidental human pathogen, we have functionally analyzed 80 Legionella genomes spanning 58 species. Uniquely, an immense r...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Gomez-Valero, Laura, Rusniok, Christophe, Carson, Danielle, Mondino, Sonia, Pérez-Cobas, Ana Elena, Rolando, Monica, Pasricha, Shivani, Reuter, Sandra, Demirtas, Jasmin, Crumbach, Johannes, Descorps-Declere, Stephane, Hartland, Elizabeth L., Jarraud, Sophie, Dougan, Gordon, Schroeder, Gunnar N., Frankel, Gad, Buchrieser, Carmen
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2019
主題:
PNAS Plus
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369783/
https://ncbi.nlm.nih.gov/pubmed/30659146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808016116
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