More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells

The genus Legionella comprises 65 species, among which Legionella pneumophila is a human pathogen causing severe pneumonia. To understand the evolution of an environmental to an accidental human pathogen, we have functionally analyzed 80 Legionella genomes spanning 58 species. Uniquely, an immense r...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Gomez-Valero, Laura, Rusniok, Christophe, Carson, Danielle, Mondino, Sonia, Pérez-Cobas, Ana Elena, Rolando, Monica, Pasricha, Shivani, Reuter, Sandra, Demirtas, Jasmin, Crumbach, Johannes, Descorps-Declere, Stephane, Hartland, Elizabeth L., Jarraud, Sophie, Dougan, Gordon, Schroeder, Gunnar N., Frankel, Gad, Buchrieser, Carmen
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369783/
https://ncbi.nlm.nih.gov/pubmed/30659146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808016116
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