Major Cancer Regressions in Mesothelioma After Treatment with an Anti-Mesothelin Immunotoxin and Immune Suppression

Immunotoxins are potent anticancer agents with an unusual mechanism of action: inhibition of protein synthesis resulting in apoptotic cell death. Immunotoxins have produced many durable complete responses in refractory hairy cell leukemia, where patients rarely form antibodies to the bacterial toxin...

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Détails bibliographiques
Publié dans:Sci Transl Med
Auteurs principaux: Hassan, Raffit, Miller, Andrew C., Sharon, Elad, Thomas, Anish, Reynolds, James C., Ling, Alexander, Kreitman, Robert J., Miettinen, Markku M., Steinberg, Seth M., Fowler, Daniel H., Pastan, Ira
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369691/
https://ncbi.nlm.nih.gov/pubmed/24154601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3006941
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