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Amitriptyline inhibits the MAPK/ERK and CREB pathways and proinflammatory cytokines through A3AR activation in rat neuropathic pain models

BACKGROUND: The pain-relief properties of tricyclic antidepressants can be attributed to several actions. Recent observations suggest that adenosine is involved in the antinociceptive effect of amitriptyline. The A3 adenosine receptor (A3AR) is the only adenosine subtype overexpressed in inflammator...

詳細記述

保存先:
書誌詳細
出版年:Korean J Anesthesiol
主要な著者: Kim, Yumi, Kwon, So Young, Jung, Hong Soo, Park, Yoo Jung, Kim, Yong Shin, In, Jang Hyeok, Choi, Jin Woo, Kim, Jin A, Joo, Jin Deok
フォーマット: Artigo
言語:Inglês
出版事項: Korean Society of Anesthesiologists 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6369348/
https://ncbi.nlm.nih.gov/pubmed/29969887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4097/kja.d.18.00022
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