Cisplatin Cytotoxicity of Auditory Cells Requires Secretions of Proinflammatory Cytokines via Activation of ERK and NF-κB

The ototoxicity of cisplatin, a widely used chemotherapeutic agent, involves a number of mechanisms, including perturbation of redox status, increase in lipid peroxidation, and formation of DNA adducts. In this study, we demonstrate that cisplatin increased the early immediate release and de novo sy...

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Detalhes bibliográficos
Main Authors: So, Hongseob, Kim, HyungJin, Lee, Jeong-Han, Park, Channy, Kim, Yunha, Kim, Eunsook, Kim, Jin-Kyung, Yun, Ki-Jung, Lee, Kang-Min, Lee, Haa-Yung, Moon, Sung-Kyun, Lim, David J., Park, Raekil
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538433/
https://ncbi.nlm.nih.gov/pubmed/17516123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-007-0084-9
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