Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats (P2) and adult Balb/C mice. Cisplatin increases the catalytic activity of caspase-3...

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Publicat a:Exp Mol Med
Autors principals: Kim, Se-Jin, Ho Hur, Joon, Park, Channy, Kim, Hyung-Jin, Oh, Gi-Su, Lee, Joon No, Yoo, Su-Jin, Choe, Seong-Kyu, So, Hong-Seob, Lim, David J, Moon, Sung K, Park, Raekil
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346486/
https://ncbi.nlm.nih.gov/pubmed/25697147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2014.112
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