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Loss of Limb-Bud-and-Heart (LBH) Attenuates Mammary Hyperplasia and Tumor Development in MMTV-Wnt1 Transgenic Mice
Canonical WNT/β- catenin signaling plays pivotal roles in mammary development and tumorigenesis; and aberrant activation of this pathway is frequently observed in human breast cancer, correlating with poor outcome. However, the mechanisms underlying WNT-mediated mammary tumorigenesis remain incomple...
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| Publicado en: | Biochem Biophys Res Commun |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368957/ https://ncbi.nlm.nih.gov/pubmed/30509497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.11.155 |
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