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Loss of Limb-Bud-and-Heart (LBH) Attenuates Mammary Hyperplasia and Tumor Development in MMTV-Wnt1 Transgenic Mice

Canonical WNT/β- catenin signaling plays pivotal roles in mammary development and tumorigenesis; and aberrant activation of this pathway is frequently observed in human breast cancer, correlating with poor outcome. However, the mechanisms underlying WNT-mediated mammary tumorigenesis remain incomple...

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Bibliographische Detailangaben
Veröffentlicht in:Biochem Biophys Res Commun
Hauptverfasser: Ashad-Bishop, Kilan, Garikapati, Koteshwararao, Lindley, Linsey E., Jorda, Merce, Briegel, Karoline J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368957/
https://ncbi.nlm.nih.gov/pubmed/30509497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.11.155
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