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Discovery and Characterization of Two Classes of Selective Inhibitors of the Suppressor of TCR Signaling Family of Proteins
The Suppressor of T cell receptor Signaling (Sts) proteins, particularly Sts-1, have recently emerged as potential immunostimulatory targets for drug development. Genetic inactivation of the Sts proteins dramatically increases host survival of systemic infection and leads to improved pathogen cleara...
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| Publicado no: | ACS Infect Dis |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368478/ https://ncbi.nlm.nih.gov/pubmed/30485744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.8b00238 |
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