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Gonadal supporting cells acquire sex-specific chromatin landscapes during mammalian sex determination

Cis-regulatory elements are critical for the precise spatiotemporal regulation of genes during development. However, identifying functional regulatory sites that drive cell differentiation in vivo has been complicated by the high numbers of cells required for whole-genome epigenetic assays. Here, we...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Garcia-Moreno, S. Alexandra, Futtner, Christopher R., Salamone, Isabella M., Gonen, Nitzan, Lovell-Badge, Robin, Maatouk, Danielle M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368449/
https://ncbi.nlm.nih.gov/pubmed/30594505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2018.12.023
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