Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of severe and irreversible central vision loss, and the primary site of AMD pathology is the retinal pigment epithelium (RPE). Geographic atrophy (GA) is an advanced form of AMD characterized by extensive RPE cell loss, subsequent degenerat...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Control Release
Auteurs principaux: Sreekumar, Parameswaran G., Li, Zhe, Wang, Wan, Spee, Christine, Hinton, David R., Kannan, Ram, MacKay, J. Andrew
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368441/
https://ncbi.nlm.nih.gov/pubmed/29778783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.05.014
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