Intra-vitreal αB crystallin fused to elastin-like polypeptide provides neuroprotection in a mouse model of age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of severe and irreversible central vision loss, and the primary site of AMD pathology is the retinal pigment epithelium (RPE). Geographic atrophy (GA) is an advanced form of AMD characterized by extensive RPE cell loss, subsequent degenerat...

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Udgivet i:J Control Release
Main Authors: Sreekumar, Parameswaran G., Li, Zhe, Wang, Wan, Spee, Christine, Hinton, David R., Kannan, Ram, MacKay, J. Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368441/
https://ncbi.nlm.nih.gov/pubmed/29778783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.05.014
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