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Toll-like receptor 3 regulates Zika virus infection and associated host inflammatory response in primary human astrocytes

The connection between Zika virus (ZIKV) and neurodevelopmental defects is widely recognized, although the mechanisms underlying the infectivity and pathology in primary human glial cells are poorly understood. Here we show that three isolated strains of ZIKV, an African strain MR766 (Uganda) and tw...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Ojha, Chet Raj, Rodriguez, Myosotys, Karuppan, Mohan Kumar Muthu, Lapierre, Jessica, Kashanchi, Fatah, El-Hage, Nazira
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368285/
https://ncbi.nlm.nih.gov/pubmed/30735502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208543
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