Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy

Here, we used a mouse model with defective autophagy to further decipher the role of Beclin1 in the infection and disease of Zika virus (ZIKV)-R103451. Hemizygous (Becn1(+/−)) and wild-type (Becn1(+/+)) pregnant mice were transiently immunocompromised using the anti-interferon alpha/beta receptor su...

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Publicado no:Viruses
Main Authors: Karuppan, Mohan Kumar Muthu, Ojha, Chet Raj, Rodriguez, Myosotys, Lapierre, Jessica, Aman, M. Javad, Kashanchi, Fatah, Toborek, Michal, Nair, Madhavan, El-Hage, Nazira
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7354588/
https://ncbi.nlm.nih.gov/pubmed/32498399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12060608
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