Morphine counteracts the antiviral effect of antiretroviral drugs and causes upregulation of p62/SQSTM1 and histone modifying enzymes in HIV-infected astrocytes

Accelerated neurological disorders are increasingly prominent among the HIV-infected population and are likely driven by the toxicity from long-term use of antiretroviral drugs. We explored potential side-effects of antiretroviral drugs in HIV-infected primary human astrocytes and whether opioid co-...

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Bibliografiske detaljer
Udgivet i:J Neurovirol
Main Authors: Rodriguez, Myosotys, Lapierre, Jessica, Ojha, Chet Raj, Pawitwar, Shashank, Karuppan, Mohan Kumar Muthu, Kashanchi, Fatah, El-Hage, Nazira
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601623/
https://ncbi.nlm.nih.gov/pubmed/30746609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-018-0715-4
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