TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis

BACKGROUND: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has previously been demonstrated to play a pro-inflammatory role in allergic airways disease and COPD through the upregulation of the E3 ubiquitin ligase MID1 and the subsequent deactivation of protein phosphatase 2A (PP2A)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Pulm Med
Prif Awduron: Collison, Adam M., Li, Junyao, de Siqueira, Ana Pereira, Lv, Xuejiao, Toop, Hamish D., Morris, Jonathan C., Starkey, Malcolm R., Hansbro, Philip M., Zhang, Jie, Mattes, Joerg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367767/
https://ncbi.nlm.nih.gov/pubmed/30732588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-019-0786-x
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