TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis

BACKGROUND: Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) has previously been demonstrated to play a pro-inflammatory role in allergic airways disease and COPD through the upregulation of the E3 ubiquitin ligase MID1 and the subsequent deactivation of protein phosphatase 2A (PP2A)...

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Detalhes bibliográficos
Publicado no:BMC Pulm Med
Main Authors: Collison, Adam M., Li, Junyao, de Siqueira, Ana Pereira, Lv, Xuejiao, Toop, Hamish D., Morris, Jonathan C., Starkey, Malcolm R., Hansbro, Philip M., Zhang, Jie, Mattes, Joerg
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367767/
https://ncbi.nlm.nih.gov/pubmed/30732588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-019-0786-x
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