RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

The molecular characterization of immune subsets is important for designing effective strategies to understand and treat diseases. We characterized 29 immune cell types within the peripheral blood mononuclear cell (PBMC) fraction of healthy donors using RNA-seq (RNA sequencing) and flow cytometry. O...

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Udgivet i:Cell Rep
Main Authors: Monaco, Gianni, Lee, Bernett, Xu, Weili, Mustafah, Seri, Hwang, You Yi, Carré, Christophe, Burdin, Nicolas, Visan, Lucian, Ceccarelli, Michele, Poidinger, Michael, Zippelius, Alfred, Pedro de Magalhães, João, Larbi, Anis
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367568/
https://ncbi.nlm.nih.gov/pubmed/30726743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.041
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