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A mixture model for expression deconvolution from RNA-seq in heterogeneous tissues

BACKGROUND: RNA-seq, a next-generation sequencing based method for transcriptome analysis, is rapidly emerging as the method of choice for comprehensive transcript abundance estimation. The accuracy of RNA-seq can be highly impacted by the purity of samples. A prominent, outstanding problem in RNA-s...

詳細記述

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書誌詳細
主要な著者: Li, Yi, Xie, Xiaohui
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622628/
https://ncbi.nlm.nih.gov/pubmed/23735186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S5-S11
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