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Automated deconvolution of structured mixtures from heterogeneous tumor genomic data

With increasing appreciation for the extent and importance of intratumor heterogeneity, much attention in cancer research has focused on profiling heterogeneity on a single patient level. Although true single-cell genomic technologies are rapidly improving, they remain too noisy and costly at presen...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Roman, Theodore, Xie, Lu, Schwartz, Russell
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695636/
https://ncbi.nlm.nih.gov/pubmed/29059177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005815
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