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Automated deconvolution of structured mixtures from heterogeneous tumor genomic data

With increasing appreciation for the extent and importance of intratumor heterogeneity, much attention in cancer research has focused on profiling heterogeneity on a single patient level. Although true single-cell genomic technologies are rapidly improving, they remain too noisy and costly at presen...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Roman, Theodore, Xie, Lu, Schwartz, Russell
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695636/
https://ncbi.nlm.nih.gov/pubmed/29059177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005815
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