Digital polymerase chain reaction for detecting c-MYC copy number gain in tissue and cell-free plasma samples of colorectal cancer patients

We focused on the utility of the droplet digital polymerase chain reaction (ddPCR) for detecting c-MYC gene copy number (GCN) gain in cell-free plasma and tumor tissue of colorectal cancer (CRC) patients. c-MYC GCN status was determined using dual-color silver in situ hybridization (SISH) and ddPCR...

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Publicat a:Sci Rep
Autors principals: Lee, Kyu Sang, Nam, Soo Kyung, Seo, Soo Hyun, Park, Kyoung Un, Oh, Heung-Kwon, Kim, Duck-Woo, Kang, Sung-Bum, Kim, Woo Ho, Lee, Hye Seung
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367402/
https://ncbi.nlm.nih.gov/pubmed/30733532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-38415-4
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