Comparative analysis of the EGFR, HER2, c-MYC, and MET variations in colorectal cancer determined by three different measures: gene copy number gain, amplification status and the 2013 ASCO/CAP guideline criterion for HER2 testing of breast cancer

BACKGROUND: The purpose of this study was to explore gene copy number (GCN) variation of EGFR, HER2, c-MYC, and MET in patients with primary colorectal cancer (CRC). METHODS: Dual-colour silver-enhanced in situ hybridization was performed in tissue samples of 334 primary CRC patients. The amplificat...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Kwak, Yoonjin, Yun, Sumi, Nam, Soo Kyung, Seo, An Na, Lee, Kyu Sang, Shin, Eun, Oh, Heung-Kwon, Kim, Duck Woo, Kang, Sung Bum, Kim, Woo Ho, Lee, Hye Seung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5540452/
https://ncbi.nlm.nih.gov/pubmed/28764718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1265-x
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