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c-MYC Copy-Number Gain Is an Independent Prognostic Factor in Patients with Colorectal Cancer

BACKGROUND: The aim of this study was to determine the incidence and clinicopathological significance of c-MYC gene copy-number (GCN) gain in patients with primary colorectal cancer (CRC). METHODS: The c-MYC GCN was investigated in 367 consecutive CRC patients (cohort 1) by using dual-color silver i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Kyu Sang, Kwak, Yoonjin, Nam, Kyung Han, Kim, Duck-Woo, Kang, Sung-Bum, Choe, Gheeyoung, Kim, Woo Ho, Lee, Hye Seung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591346/
https://ncbi.nlm.nih.gov/pubmed/26426996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139727
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