ROLE of IGF-1 System in the Modulation of Longevity: Controversies and New Insights From a Centenarians' Perspective

Human aging is currently defined as a physiological decline of biological functions in the body with a continual adaptation to internal and external damaging. The endocrine system plays a major role in orchestrating cellular interactions, metabolism, growth, and aging. Several in vivo studies from w...

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Bibliographic Details
Published in:Front Endocrinol (Lausanne)
Main Authors: Vitale, Giovanni, Pellegrino, Giuseppe, Vollery, Maria, Hofland, Leo J.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Endocrinology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6367275/
https://ncbi.nlm.nih.gov/pubmed/30774624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2019.00027
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