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Opportunities and challenges for the use of induced pluripotent stem cells in modelling neurodegenerative disease
Adult-onset neurodegenerative diseases are among the most difficult human health conditions to model for drug development. Most genetic or toxin-induced cell and animal models cannot faithfully recapitulate pathology in disease-relevant cells, making it excessively challenging to explore the potenti...
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| Pubblicato in: | Open Biol |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6367134/ https://ncbi.nlm.nih.gov/pubmed/30958120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180177 |
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