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Absence of LTBP-3 Attenuates the Aneurysmal Phenotype But Not Spinal Effects on the Aorta in Marfan Syndrome
Fibrillin-1 is an elastin-associated glycoprotein that contributes to the long term fatigue resistance of elastic fibers as well as to the bioavailability of transforming growth factor-beta (TGFβ) in arteries. Altered TGFβ bioavailability and/or signaling have been implicated in aneurysm development...
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| Publicado no: | Biomech Model Mechanobiol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6367053/ https://ncbi.nlm.nih.gov/pubmed/30306291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10237-018-1080-1 |
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