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Evidence for Weak Selective Constraint on Human Gene Expression
Gene expression variation is a major contributor to phenotypic variation in human complex traits. Selection on complex traits may therefore be reflected in constraint on gene expression. Here, we explore the effects of stabilizing selection on cis-regulatory genetic variation in humans. We analyze p...
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| Publicado no: | Genetics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6366908/ https://ncbi.nlm.nih.gov/pubmed/30554168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.118.301833 |
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