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Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium

Within-host adaptation of pathogens such as human immunodeficiency virus (HIV) often occurs at more than two loci. Multiple beneficial mutations may arise simultaneously on different genetic backgrounds and interfere, affecting each other's fixation trajectories. Here, we explore how these evol...

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Detalhes bibliográficos
Publicado no:J R Soc Interface
Main Authors: Garcia, Victor, Glassberg, Emily C., Harpak, Arbel, Feldman, Marcus W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908532/
https://ncbi.nlm.nih.gov/pubmed/29563246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2017.0921
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