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Clonal interference can cause wavelet-like oscillations of multilocus linkage disequilibrium
Within-host adaptation of pathogens such as human immunodeficiency virus (HIV) often occurs at more than two loci. Multiple beneficial mutations may arise simultaneously on different genetic backgrounds and interfere, affecting each other's fixation trajectories. Here, we explore how these evol...
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| Udgivet i: | J R Soc Interface |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5908532/ https://ncbi.nlm.nih.gov/pubmed/29563246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2017.0921 |
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