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Novel Multilocus Measure of Linkage Disequilibrium to Estimate Past Effective Population Size

Linkage disequilibrium (LD) between densely spaced, polymorphic genetic markers in humans and other species contains information about historical population size. Inferring past population size is of interest both from an evolutionary perspective (e.g., testing the “out of Africa” hypothesis of huma...

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Detalhes bibliográficos
Main Authors: Hayes, Ben J., Visscher, Peter M., McPartlan, Helen C., Goddard, Mike E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC430161/
https://ncbi.nlm.nih.gov/pubmed/12654718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.387103
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