ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition

Some cancer cells elongate their telomeres through the ALT (alternative lengthening of telomeres) pathway, which is based on homologous recombination for the addition of telomere repeats without telomerase activity. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF), tw...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Bakhos-Douaihy, Dalal, Desmaze, Chantal, Jeitany, Maya, Gauthier, Laurent R., Biard, Denis, Junier, Marie-Pierre, Chneiweiss, Hervé, Boussin, François D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2019
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366824/
https://ncbi.nlm.nih.gov/pubmed/30774779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26616
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