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ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition

Some cancer cells elongate their telomeres through the ALT (alternative lengthening of telomeres) pathway, which is based on homologous recombination for the addition of telomere repeats without telomerase activity. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF), tw...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Bakhos-Douaihy, Dalal, Desmaze, Chantal, Jeitany, Maya, Gauthier, Laurent R., Biard, Denis, Junier, Marie-Pierre, Chneiweiss, Hervé, Boussin, François D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366824/
https://ncbi.nlm.nih.gov/pubmed/30774779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26616
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