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ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition
Some cancer cells elongate their telomeres through the ALT (alternative lengthening of telomeres) pathway, which is based on homologous recombination for the addition of telomere repeats without telomerase activity. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF), tw...
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| Gepubliceerd in: | Oncotarget |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Impact Journals LLC
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6366824/ https://ncbi.nlm.nih.gov/pubmed/30774779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26616 |
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