ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition

Some cancer cells elongate their telomeres through the ALT (alternative lengthening of telomeres) pathway, which is based on homologous recombination for the addition of telomere repeats without telomerase activity. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF), tw...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Bakhos-Douaihy, Dalal, Desmaze, Chantal, Jeitany, Maya, Gauthier, Laurent R., Biard, Denis, Junier, Marie-Pierre, Chneiweiss, Hervé, Boussin, François D.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366824/
https://ncbi.nlm.nih.gov/pubmed/30774779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26616
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