Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance

Cancer cells can use a telomerase-independent mechanism, known as alternative lengthening of telomeres (ALT), to elongate their telomeres. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF) are two homologous acetyltransferases that are mutually exclusive subunits in SA...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Jeitany, Maya, Bakhos-Douaihy, Dalal, Silvestre, David C., Pineda, Jose R., Ugolin, Nicolas, Moussa, Angela, Gauthier, Laurent R., Busso, Didier, Junier, Marie-Pierre, Chneiweiss, Hervé, Chevillard, Sylvie, Desmaze, Chantal, Boussin, François D.
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432255/
https://ncbi.nlm.nih.gov/pubmed/28412741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15447
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