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Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance
Cancer cells can use a telomerase-independent mechanism, known as alternative lengthening of telomeres (ALT), to elongate their telomeres. General control non-derepressible 5 (GCN5) and P300/CBP-associated factor (PCAF) are two homologous acetyltransferases that are mutually exclusive subunits in SA...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5432255/ https://ncbi.nlm.nih.gov/pubmed/28412741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15447 |
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