Structure basis of neutralization by a novel site II/IV antibody against respiratory syncytial virus fusion protein

Globally, human respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in newborns, young children, and the elderly for which there is no vaccine. The RSV fusion (F) glycoprotein is a major target for vaccine development. Here, we describe a novel monoclonal antib...

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Veröffentlicht in:PLoS One
Hauptverfasser: Xie, Qingqing, Wang, Zhao, Ni, Fengyun, Chen, Xiaorui, Ma, Jianpeng, Patel, Nita, Lu, Hanxin, Liu, Ye, Tian, Jing-Hui, Flyer, David, Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Wang, Qinghua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6366758/
https://ncbi.nlm.nih.gov/pubmed/30730999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210749
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