Respiratory Syncytial Virus Fusion Glycoprotein Expressed in Insect Cells Form Protein Nanoparticles That Induce Protective Immunity in Cotton Rats

Respiratory Syncytial Virus (RSV) is an important viral agent causing severe respiratory tract disease in infants and children as well as in the elderly and immunocompromised individuals. The lack of a safe and effective RSV vaccine represents a major unmet medical need. RSV fusion (F) surface glyco...

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Detalhes bibliográficos
Main Authors: Smith, Gale, Raghunandan, Rama, Wu, Yingyun, Liu, Ye, Massare, Michael, Nathan, Margret, Zhou, Bin, Lu, Hanxin, Boddapati, Sarathi, Li, Jingning, Flyer, David, Glenn, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511306/
https://ncbi.nlm.nih.gov/pubmed/23226404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050852
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